Photoshop loads all fonts installed on your machine when the application starts. Loading 4800 fonts eats up a lot of resources. Not to mention that all those fonts are kept in memory until you quit Photoshop, thus the application becomes very slow.
There might be some workarounds for this, you could try searching Google.
Related link.
Here's what Adobe says about optimizing performance in Photoshop.
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quote:
Use font management software and turn off the WYSIWYG font list
Your computer can slow down if there are too many active fonts on the system. Font management software allows you to deactivate the fonts you aren't using to speed up the computer. Turning off the WYSIWYG font preview list will also speed the processing of fonts in Photoshop.
To turn off the font preview:
1. Open Photoshop.
2. Choose Edit > Preferences > Type.
3. Deselect Font Preview Size and close Preferences.
Hope it helps.