Shoutbox

A person sent me what I though a good program I opened it and it just disappeared next thing I know this funny symbol appears in the right bottom of the screen and I highlight it and it says, "your computer my be affected with harmful or unwanted software!" Also whenever I go onto my homepage it goes onto a strange website called http://www.ieuptodate.com/ 
Another thing is all these naughty popups keep coming up and It is not in the add and remove program list. I have used my Zone Alarm and ewido and thats no help. I have another copy of that program that person sent me but its too dangerous to open.

I ahve posted a screenshot below to help, the red icon with the exclaimation mark and the yellow one came when I clicked on the program.