Yup, I've confirmed it now.
It's from the patch! I was "testing" some things here when I got this message saying that an external program was interfering with Plus.
Thank you all for the help
EDIT: Tested another funny thing. I ran into the old instaler from my previous version of Plus, and installed it. Everything went back to normal, now I'm certain, I'll have to leave a-patch behind when I update everything and get it running well again