http://gifpaste.org/eddie/
That's just to demonstrate a 3-column layout. It takes very little CSS and even less HTML to make it work. I tested it in Firefox, Chrome, IE (7, 8), and Opera.
Right now it's fixed-width at 800px, but it only takes a tiny change to make it fluid with the center column expanding as the page does (simply make the width a percentage, or remove it altogether and use the margin to center it.. whatever you want).
The only issue is it doesn't seem to center correctly in IE7 (that's IE for you), and I'm not in the mood to look into why right now.
