Quote: "Huevos grrrandes amigou" (US-accent)
Actor/Character: Michael Clarke Duncan as Franklin 'Frankie Figs' Figueroa
Movie: The whole nine yards
Why: Hey, have you ever herd his deeeeep voice?
How: on DVD
Possible situation which makes it funny/sad or whatever: The main char., an innocent dentist involved accidentally in mafia, is about to change the toothing between Bruce Willis and a death gangster. He's obviously afraid and nervous.
But this isn't bad either: