Well, I don't like much the amount of memory it sucks, the time it takes to load (even when restoring it from running in background or minimized) and the load it gets when you open the extensions panel: it freezes a couple of minutes before reacting (Athlon2800+, 256MB, XP/Pro).
There are indeed some things to improve, but all the rest is really good: costumizable, open-source, free, fast, with many good features...
It will be very good when it reaches the final release and it will be able to compete seriously with IE.
Btw, Garndell: the CERT suggested not to use IE and try out alternate browsers that may not be much more safe, but aren't an exploit target right now (
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