RE: Serpop.exe
I have VB2K5 Ex., but I don't have this file. It's unlikely to be the output of one of the programs you've made as well.
Since Windows XP, very few programs put files in C:\WINDOWS - I have 6 windows exes and a bunch of uninstallers in this folder.
Personally, I think it's dodgy. It's likely to be minor malware - ie. it's not so much a virus as an annoyance, or a backdoor for other virii to come in.
Reboot to safe mode, rename it, see if everything still works, if it does, just leave it renamed.
You could also try running an AdAware scan, or something similar.
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