Shoutbox

Have you tried fully uninstalling and reinstalling Plus?
Uninstall Plus and remove all your preferences when asked to (you can back them up and try restoring them later). Remove Plus directory (usually C:\Program files\Messenger Plus! 3). Now go to Start > Run, type "regedit" and click OK.
Browse to HKEY_LOCAL_MACHINE\Software\Patchou and press Del to delete it. Now browse to HKEY_CURRENT_USER\Software\Patchou and do the same. Reinstall Plus and check what happens.