To start, a big correction: that isn't a serial connector but a gameport connector, it is quite different than a serial RS232 connector.
Anyways, it all depends...
There are Gameport to USB and vice versa converters. Somem might require additional software, some not. It might work on some joysticks and on some not, it might work on your PC, it might not, it might work with that game, but not with the other... etc...etc...etc...
The only thing you can say with certainty is that Gameport to USB and vice versa converters exist... But you're probably better of buying a joystick with the correct connector in the first place (and it would cost you probably less)
The only thing you can do is try it out (but that would most likely require you to buy some converter plug with the chance it doesn't work with that, so...)
quote:
Originally posted by atown44
(cut + twist + electric tape)
erm.. if this is what you're going todo then no, it will absolutely not work at all. The hardware behind both connectors work in a completely different way and are incompatible without converters of the protocols being used. If you just are going to rewire it to another connector the chances are extremely high you will actually screw up the joystick, the usb port and maybe even your computer because of shortcuts.
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